European Food Safety Authority Reviews, Rebukes Ayyadurai Claim of Formaldehyde in GMO Soy

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PUBLISHED: 03 November 2015
www.efsa.europa.eu/publications EFSA Supporting publication 2015:EN-885

EFSA scientific advice to EC on new scientific information in relation to the risk assessment of genetically modified organisms European Food Safety Authority

Abstract
Following a request of the European Commission, the European Food Safety Authority (EFSA) reviewed a recent publication by Ayyadurai and Deonikar, 2015 (Do GMOs Accumulate Formaldehyde and Disrupt Molecular Systems Equilibria? Systems Biology May Provide Answers). The main arguments presented by the authors were the significant accumulation of formaldehyde and concomitant depletion of glutathione in Roundup Ready soybeans due to the genetic modification when applying computational model simulation of important biological pathways. EFSA considers that the applied computer model is exclusively based on theoretical considerations, and that no empirical evidence is provided to support the model predictions.

EFSA addressed one-by-one the technical issues involved, related to the model chosen, the lack of empirical data, and accumulation of formaldehyde and concomitant depletion of glutathione. Considering that the authors do not provide information on the input data and the algorithm used in the model, that the model is not validated, and that no empirical studies have been presented to support the predictions of the model, EFSA is of the opinion that the author’s conclusions are not supported. Therefore, EFSA considers that its previous risk assessment conclusions on EPSPS expressing herbicide tolerant GM soybean events remain valid.

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An article written more in layman’s terms by the Genetic Literacy Project can be read here.