Cows Made Hornless Through Gene-Editing, With No Off-Target Effects

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Physical dehorning of cattle is a common practice. This practice is considered necessary to prevent cattle from injuring each other or injuring farm workers. “Dehorning animals is a bloody and painful process that no one likes to do, and horns are a danger to those working with the animals. ”

Scientists were able identify a genetic variation in hornless cattle and incorporate it into calf genomes. The scientists report that they found off-target effects. Several researchers comment about the value of this application of genetic engineering.